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    HomePRODUCTSLife ScienceOsrhKGF Recombinant Human Keratinocyte Growth Factor

    OsrhKGF Recombinant Human Keratinocyte Growth Factor

    Cell Culture Grade

     

    • Source: Rice Grain (Oryza Sativa)

    • CAt No: HYC027M01

    • Appearance: White lyophilized powder 

    • Package: 10ug，50ug, 1mg and 10mg

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    • Detailed Description
    • FAQ

    • Product Description

      Keratinocyte growth factor (KGF) , also known as FGF-7, is a member of FGF family. It is a cytokine discovered in the culture supernatant of embryonic lung fibroblasts. KGF, an effective epithelial cell-specific growth factor, is secreted by mesenchymal cells and its receptor is distributed in epithelial cells. Its mitotic activity is mainly manifested in keratinocytes, which can specifically stimulate the proliferation, migration and differentiation of epithelial cells. It also closely relate to organ development, wound healing, tumorigenesis and immune reconstruction etc.
       

      OsrhKGF, expressed in the rice endosperm platform and purified by chromatography, is animal component free and has high biological activity. The rice endosperm platform makes the manufacture capability at hundreds of gram scales to meet your bulk bioprocessing needs.

      Advantages of OsrHSA Application in Medical Devices

      Chemical Defined & Animal-Free;
      High Batch-to-Batch Consistancy;
      Stable Bulk Supply
      cGMP Manufactured
      DMF(No.29648)

      Why Select OsrHSA Over Yeast- and Plasma-Sourced Albumin

       Items OsrHSA (rice-derived) ScrHSA (yeast-derived)
      Safety Free of animal, Virus, Pathogene, low endotoxin Possible residual yeast cell wall components (such as B-glucan),additional removal of endotoxins required
      Post-translational modifications No glycosylation modification, structure identical to native HSA Glycosylation modification, Risk of inclusion formation requires reproducibility
      Production process Simple process with Three-step chromatography purification High-density fermentation is costly, with more complex production process
      Scale up Low-cost in rice cultivation
      Long-term stable storage in rice seeds
      Single-batch purification cycle: 24h
      Low immunogenicity, suitable for stem/primary cells, high batch
      consistency      		 High capital investment for fermentation equipmentSingle-batch production cycle:3-7 days
      Residual host proteins affect cell growth, batch difference exists
      Cell culture compatibility
      Regulation and ethics Comply with regulations and shorten the filing time, environmentally fri
      endly and sustainable      		 Microbial fermentation requires strict GMP control, Acceptance of genetically modified yeast
      varies by region

      Application

      Virus vaccine production
      Cell therapy & Gene therapy
      In vitro fertilization cryopreservation
      Regenerative medicine& Tissue storage
      Medical Source coating & Surgical sealants

      • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

        Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

      • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

        Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

      • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

        Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

      • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

        Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

    Tags:

    Recombinant Human Serum Albumin

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