HomePRODUCTSLife ScienceOsrHSA Advance—Recombinant human albumin

OsrHSA Advance—Recombinant human albumin

Cell Culture Grade

 

• Source: Rice Grain (Oryza Sativa)

• CAt No: HYC002M01, HYC002M02, HYC002M03

• Appearance: Light yellow to white or greyish-whitepowder or crystalline powder

• Package: 1g, 10g, 50g ,100g and 1000g

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  • Detailed Description
  • FAQ
  • Product Description

    In recent years, there has been an increased demand for animal-free components to replace serum or animal originated supplements to eliminate the risk of viruses and mycoplasma contaminants. Using the rice endosperm specific expression platform, the OsrHSA Advanced, which is animal component free, can provide an economical and safe approach for the production of non–animal-derived compounds.

    Advantages of OsrHSA Application in Medical Devices

    Chemical Defined & Animal-Free;
    High Batch-to-Batch Consistancy;
    Stable Bulk Supply
    cGMP Manufactured
    DMF(No.29648)

    Why Select OsrHSA Over Yeast- and Plasma-Sourced Albumin

     Items OsrHSA (rice-derived) ScrHSA (yeast-derived)
    Safety Free of animal, Virus, Pathogene, low endotoxin Possible residual yeast cell wall components (such as B-glucan),additional removal of endotoxins required
    Post-translational modifications No glycosylation modification, structure identical to native HSA Glycosylation modification, Risk of inclusion formation requires reproducibility
    Production process Simple process with Three-step chromatography purification High-density fermentation is costly, with more complex production process
    Scale up Low-cost in rice cultivation
    Long-term stable storage in rice seeds
    Single-batch purification cycle: 24h
    Low immunogenicity, suitable for stem/primary cells, high batch
    consistency
    High capital investment for fermentation equipmentSingle-batch production cycle:3-7 days
    Residual host proteins affect cell growth, batch difference exists
    Cell culture compatibility
    Regulation and ethics Comply with regulations and shorten the filing time, environmentally fri
    endly and sustainable
    Microbial fermentation requires strict GMP control, Acceptance of genetically modified yeast
    varies by region

    Application

    Virus vaccine production
    Cell therapy & Gene therapy
    In vitro fertilization cryopreservation
    Regenerative medicine& Tissue storage
    Medical Source coating & Surgical sealants

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

    • Do you have any comparison data between your OsrHSA and plasma derived human serum albumin (pHSA)? Is there any difference?

      Yes, we do. From our comparative test, OsrHSA is structurelly and biochemically equivalent to pHSA, and functions equivalently to pHSA in terms of binding capacity and promotion of cell growth. In addition, OsrHSA displays the same immunogenicity as pHSA.

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