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OsrHSA (Recombinant Human Serum Albumin from *Oryza sativa*) was developed by Hedygen through its patented rice endosperm cell protein expression platform (OryzHiExp ) and is produced in an automated, digitized, and intelligent biopharmaceutical manufacturing facility utilizing DCS and MES systems.

  • Vectors construction

  • Genetic transformation

  • Plant regeneration

  • Endosperm-specificexpression

  • Large-scale production

  • Extraction and purification

  • Final products

Wuhan Healthgen Biotechnology Corp. (Healthgen Biotech), specializing in molecular pharmaceutical research and development, is a private company founded in 2006. We are focusing on developing, manufacturing and marketing a series of environmental friendly and safe products by using the State-of-the-Art platform called Oryzᴴⁱᴱˣᵖ, having high capacity to express proteins or small peptides in the rice grain.

Oryzᴴⁱᴱˣᵖ A Rice endosperm specific expression platform

Using the Oryzᴴⁱᴱˣᵖ platform, Healthgen Biotech maximizes the innovative animal-free product development opportunities for clients and partners. Its cost-effective expression capability made it as a breakthrough expression platform.

Oryz a Rice endosperm specific expression platform

Using the Oryzᴴⁱᴱˣᵖ platform, Healthgen Biotech maximizes the innovative animal-free product development opportunities for clients and partners. Its cost-effective expression capability made it as a breakthrough expression platform.

Why

Rice

  • High Expression Level

    Patented promotor enable the expression level is 10~100 times higher over other expression system.

  • Cost-Effective

    Rice endosperm platform is cost effective for early stage companies. No enormous investment of bioreactor tanks in the enlarged stage.

  • Scale-Up Easily

    The rice is scaled up by farming, and purified recombinant proteins or peptides can reach kilo grams level with 2 years.

  • High Bioactivity

    The recombinant proteins or peptides is expressed in the rice endosperm and stored in the rice protein body which can keep the protein stability and bioactivity to the maximum extent.

  • Chemical Defined

    Free of animal-origin pathogens, can eliminate or reduce the potential risk of viruses and other unknown factors in blood derived products.

  • Environment-Friendly

    Rice raw materials are produced through photosynthesis without undergoing fermentation.

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